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Genetics in the development of type 1, type 2, and gestational diabetes

There are many health conditions that are said to be hereditary because they can be passed from parents to their children. diabetes This is one of those diseases that tends to run in families. Genetics play a significant role in the development of diabetes, a complex and widespread health condition that affects millions of individuals worldwide. While lifestyle factors such as diet and physical activity are widely recognized as important determinants of diabetes risk, genetic factors also contribute significantly to a person’s susceptibility to the disease. Understanding the interplay between genetics and diabetes is essential to improve prevention, diagnosis, and treatment strategies.

Role of genetics in type 1 and type 2 diabetes:

According to Dr. Bir Singh Sehrawat, who is the Director and HOD of Gastroenterology at Marengo Asia Hospital, Faridabad, “As far as the role of genetics is concerned, genetic mutations due to diabetes Involve the proteins responsible for insulin production or the body’s ability to use insulin. However, these mutations cause the protein to function incorrectly.”

“type 1 diabetes It is an autoimmune condition where the body’s immune system destroys the insulin-producing cells in the pancreas. Some research has shown that people with certain genetic markers are more likely to develop type 1. diabetes, These genetic markers are often associated with the immune system and regulation of immune responses. If someone has a close family member with type 1 diabetesShe is more vulnerable to developing the disease,” he said.

Talking about type 2 diabetes, Dr. Bir Singh Sehrawat said, “Genetic variants can affect the way your body processes glucose, insulin and fat, making you more likely to develop insulin resistance and other metabolic disorders of type 2. Become more sensitive towards related issues. diabetes, People are more likely to develop type 2 diabetes If they have certain conditions such as prediabetes, multiple gene mutations associated with type 2 diabetesfamily history of diabetesHave been diagnosed with high blood pressure, are over 45, are overweight, are less physically active, are pregnant diabetes ,diabetes while pregnant) have given birth to a baby who weighs more than 9 pounds, have low levels of HDL, called “good cholesterol,” have high levels of triglycerides, have depression, have a history of heart disease or stroke And polycystic ovary syndrome (PCOS).”

Role of genetics in the development of gestational diabetes:

gestation period diabetes Develops during pregnancy, particularly affecting how the body handles glucose (sugar). Genetics may increase the risk of this condition. If a person has a family history diabetes (especially type 2 diabetes), is more likely to develop during pregnancy diabetes, There are certain genetic factors that affect the way glucose and insulin are processed in the body. These genetic factors can cause gestational growth diabetes, If anyone has a personal history of pregnancy diabetes During a previous pregnancy, the risk of it developing again in the next pregnancy is higher. Other factors such as hormonal changes during pregnancy, weight gain and lifestyle factors also play an important role. Therefore it is advisable to maintain a healthy lifestyle including a balanced diet and regular physical activity as it can help reduce the risk of gestational growths. diabetesEven if you have a genetic predisposition.

Importance of genetic testing to identify increased risk of diabetes:

Dr. Gurjada Kalyan Chakraborty, an endocrinologist at Citizens Specialty Hospital, Hyderabad, said, “Genetic testing has become increasingly important in identifying individuals at high risk of diabetes. Understanding one’s genetic predisposition allows individuals to adjust their lifestyle. Can be empowered to engage and make informed decisions about options.” Preventive measures include maintaining a healthy weight and eating a balanced diet.”

The future of personalized diabetes care:

Dr Divya Singh, who is a senior surgeon at Ram Manohar Lohia Hospital and director of Maiya Social Change Front Foundation, said, “Advances in genetic research have paved the way for personalized medicine in diabetes care. By identifying, health care can be provided.” Providers can offer tailored treatment plans and lifestyle recommendations to reduce the risk of developing diabetes and complications. Genetic testing is becoming more accessible, allowing individuals to gain information about their genetic predisposition to diabetes. “As our understanding of the genetic basis of diabetes continues to expand, personalized approaches to prevention and management are on the horizon, providing new hope in the fight against this widespread health challenge.”

(Disclaimer: The information provided in the article, including treatment suggestions shared by doctors, is for general informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified person regarding any medical condition. healthcare provider for any questions you may have regarding.)



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